USDA-agricultural research service scientists recently applied for a patent on a cloned gene that produces CD14 and its application for treating and preventing mastitis. Discovered several years ago, CD14 is a naturally occurring protein in cows’ milk and blood that binds and neutralizes endotoxins, like those from Escherichia coli. This action protects cows from shock and reduces clinical symptoms of coliform mastitis. And in trials, CD14 has been perfect in preventing mastitis caused by E.coli.

Researchers are hard at work on this delivery system, and are seeking business partners to license the technology and produce CD14.

For more information contact dairy scientist Max Paape at: mpaape@anri.barc.usda.gov