FADRU molecular biologist Peter Krug designed tests to validate the cell line by comparing it to other cell types using virus samples from animal tissues. The new cell line proved to be faster and more reliable than all current diagnostic cell lines in detecting virus in FMD-infected cattle and pig tissue samples from numerous countries.
"Other cell types currently used to diagnose FMD don't survive long and have to be obtained directly from animals as primary cell cultures, causing variation from one batch to the other," Rodriguez said. "This new cell line can be continually grown in culture, maintains susceptibility to FMDV much longer, and doesn't require getting new cells from animals repeatedly."
Scientists have applied for a patent on the new cell line and are making plans to distribute it to diagnostic laboratories in the United States and other countries.