Last week the U.S. Food and Drug Administration issued a draft guidance intended to help reduce the development of resistance to medically important antimicrobial drugs used in food-producing animals.
The question becomes what does this mean to animal agriculture. Here is what three experts shared on AgriTalk this week.
“There is concern at FDA regarding antibiotic use in livestock,” William Flynn told AgriTalk radio. Flynn is the Sr. advisor for science policy at the FDA center for veterinary medicine. “The broader public concern is about antimicrobial resistance, in general terms drugs becoming less effective because bacteria become resistant to them.” Flynn said that antibiotic resistance is contributed to by all different uses of antibiotics, including use in humans as well as animal agriculture. But the guidance released by FDA is specific to antibiotic usage in animal agriculture.
Flynn says the FDA is not looking at this from a perspective of moving to ban antibiotics or stop the use of antibiotics all together. The FDA is trying to look at how antibiotics are used and trying to make sure antibiotics are used as judiciously as they can be. “We believe if we can limit how antibiotics are used it will slow down the process by which resistance emerges,” note Flynn.
A key element of this document is that it is going out as a draft and the FDA is very interested in receiving input from all stakeholders, in particular from producers and veterinarians, who rely on these antibiotics, says Flynn. “This is really the very beginning of the process. The draft guidance is now out there and we are in a 60-day public comment period right now. We’re going to look closely at all the comments we receive.”
When asked if Flynn had any documented proof that the use of antibiotics in livestock had any adverse affects on human health, he responded by saying he believes there is sufficient concern to take some steps to address the issue of antimicrobial drug resistance.
The National Pork Producers Council says more study needs to be done before implementing any changes in antibiotic use in livestock because no studies yet show a link to human antibiotic resistance.
“I know that FDA and others who support this say there is plenty of science, but what their talking about is that there is plenty of science to say that antibiotic use leads to antibiotic resistance, that’s a fact because bacteria evolve. There is no science that says antibiotic use in livestock leads to antibiotic resistance in humans. We don’t see the science there to take away some very important animal health products,” Dave Warner, director of communications for the National Pork Producers Council told AgriTalk radio.
“I think FDA is using the precautionary principle ‘we think that it might be a problem, we’re going to do something about it, regardless of whether it does or does not cause a problem’,” says Warner.
If the guidance goes forward as it is now, Warner says there could be some animal health products eliminated. “It could eliminate products we know prevent disease in the way we use them right now and under this guidance we wouldn’t be able to use them anymore. That’s going to be a problem,” says Warner. He says we’re going to end up with animals that are not as healthy, that may become sick. “Certainly we will have treatment options available. But we have studies that show animals that have been sick during its lifetime have higher incident of food borne pathogens than those that haven’t been sick.”
Bottom line we want all the tools available to keep our animals healthy, because healthy animal produce safe food, says Warner.
Christine Hoang of the American Veterinary Medical Association says the AVMA will work with FDA on developing guidelines for antibiotic use, but more study needs to be done to determine both effectiveness and risk.
For more information read: FDA issues draft guidance on antimicrobials
Recently the American Association of Bovine Practitioners and the Academy of Veterinary Consultants responded to the FDA draft guidance on antimicrobials. Both organizations remain committed to regulation based on data-based analysis rather than expert consensus. Read: AABP and AVC respond to FDA draft guidance on antimicrobials