Intervet/Schering-Plough Animal Health announces the reintroduction of the Vista® vaccine line, which provides dairy veterinarians and producers with protection against the most common and costly bovine respiratory and reproductive diseases.

Vista vaccines protect against Infectious Bovine Rhinotracheitis (IBR), Bovine Viral Diarrhea (BVD Type 1 and Type 2), Parainfluenza3 (PI3), Bovine Respiratory Syncytial Virus (BRSV), leptospirosis, vibriosis, Mannheimia haemolytica and Pasteurella multocida.

Vista was first available in July 2005. After four years, Vista was voluntarily taken off the market because of a variability issue with the BRSV antigen. By changing the stabilizer and improving the manufacturing process of the BRSV antigen, the variability issue was resolved, and Vista has been approved by the U.S. Department of Agriculture to return to the marketplace.

“Intervet/Schering-Plough Animal Health is committed to providing innovative, high-quality animal-health products that dairy veterinarians and producers trust,” says Jeff Baxter, senior marketing manager for cattle vaccines for Intervet/Schering-Plough Animal Health. “We are excited to reintroduce Vista to our portfolio of products and are confident it will deliver the protection needed to keep dairy animals healthy and productive.”

Vista provides protection from bovine respiratory disease (BRD), more commonly known as pneumonia, which is the most important disease in calves older than 30 days. Long-term effects of pneumonia include a negative impact on growth, reproductive performance, milk production and longevity.

Vista provides the following respiratory health benefits to cattle:

  • The only avirulent-live Mannheimia haemolytica/Pasteurella multocida protection combined with a modified-live viral (MLV) five-way viral.
  • 182-day duration of immunity (DOI) for IBR and 206- and 200-day DOI for BVD Type 1 and Type 2, respectively.
  • BRSV protection in a single-dose.
  • Proven cell-mediated immunity (CMI) response to IBR, BVD Type 1 and Type 2 and BRSV viruses.

Vista Once SQ is the only avirulent-live Mannheimia haemolytica/Pasteurella multocida protection combined with a MLV five-way viral. Mannheimia haemolytica and Pasteurella multocida are common causes of BRD, and Vista’s unique avirulent-live technology helps lead to a more complete immune response.

“Vista’s avirulent-live M. haemolytica and P. multocida fractions provide an immune response that more closely simulates that occurring in natural infection,” says Scott Nordstrom, D.V.M., director of dairy technical services for Intervet/Schering-Plough Animal Health. “This provides a more comprehensive level of immunity compared to killed vaccines. In addition, its non-adjuvented formulation reduces reactions and minimizes tissue damage.”

And, Vista provides protection from reproductive diseases in cattle, including leptospirosis, vibriosis, IBR and BVD Type 1 and Type 2. Reproductive diseases result in poor conception rates, occasional abortions and reduced calving percentages.

Vista provides the following reproductive health benefits to cattle:

  • 217-day DOI for IBR and 206-day DOI for BVD Type 1 and Type 2.
  • Persistent and fetal (congenital) protection for BVD Type 1 and Type 2.
  • Protection against Leptospira hardjo, including L. borgpetersenii serovar hardjo-bovis -- available in a five-way viral/five-way Lepto combination.
  • IBR abortion protection
  • Prevention of L. hardo-bovis urinary shedding.
  • Single-dose L. hardjo-bovis protection.
  • Campylobacter fetus protection.

Vista provides BVD Type 1 and Type 2 protection throughout the entire pregnancy, offering complete fetal protection. Vista is labeled for both persistent infection, for less than 120 days of gestation, and for fetal (or congenital) infection, after 120 days of gestation.

“The fetal infection label claim is important to protect the fetus during the entire pregnancy and not just the first 120 days,” Nordstrom says. “Research has demonstrated that if a cow contracts an acute BVD infection after 120 days of pregnancy, the virus still can infect the unborn calf and have devastating effects.”

“Infected animals may not live through the pregnancy, may be born with congenital abnormalities or be born looking perfectly normal,” Nordstrom says. “However, these calves can get acutely sick more than twice as often as unaffected calves, and heifers can be delayed in getting pregnant.”

Source: Intervet/Schering-Plough Animal Health