Successfully heat-treating colostrum requires adherence to strict protocols, according to University of Minnesota researchers led by Sandra Godden. To avoid excessive IgG loss while preventing extreme thickening, they advise:
- Control temperature precisely.
- Prevent temperature from fluctuating more than 1°C above the target of 60°C.
- Heat and cool colostrum rapidly and actively before and after the holding phase of 60°C for 60 minutes.
- Constantly agitate colostrum during the heating up, holding and cooling down phases of the process.






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